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Folklore

Open Source

Clinical variant interpretation with ACMG/AMP classification and public evidence

  • Artificial intelligence
  • Bulgaria
  • #16This week in Artificial intelligence
  • 0Upvotes
  • 17 days leftLive until 02/10/2026

Overview

Folklore is Helena Bioinformatics' main software product and public read-only MCP server for clinical variant interpretation.

It supports ACMG/AMP classification and retrieval of public evidence and biomedical literature for supported GRCh38 germline variants. It is built for researchers and qualified professionals, does not accept patient data, and does not replace professional review.

  • Artificial intelligence

Trust

Vendor-provided details with clear sources for buyer review

DPANot available
HostingEuropean Union
Data residencyEuropean Union
Self-hostingAvailable
Open sourceSource-available
APIAvailable